San Francisco 49ers @ LA Rams: Same Game Parlay 9/10/2026

The 49ers and Rams renew one of the NFL’s best divisional rivalries tonight in Melbourne, with San Francisco holding a narrow all-time edge. The Rams won the most recent meeting 42-26, while each team has won three of the last six. This is a big early statement game and our Same Game Parlay pick reflects that!

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Kyren Williams Over 1.5 Receptions

Kyren Williams caught 36 passes in 2025. The over on him has hit in 5 consecutive games, the 49ers ranked 3rd for Receptions allowed to RB last season and 5th for Receptions allowed overall.

Christian McCaffrey Over 4.5 Receptions

Christian McCaffrey caught 102 passes in 2025. He's cashed on the over 4 times in 5 games, the Rams allowed the 6th most Receptions last season to RBs and the 7th most Receptions overall.

Kyren Williams Over 11.5 Receiving Yards

Kyren Williams had 281 receiving yards in 2025. He's cashed on the over in 5 straight games, San Francisco ranked 10th for Receiving Yards allowed to opposing RBs last season. Williams has also cleared this line 3 times in 5 head-to-head meetings with the 49ers.

Matthew Stafford Over 1.5 Passing Touchdowns

Matthew Stafford threw for 46 touchdowns in 2025. The over on him has cashed 4 times in 5 games, the 49ers ranked 12th for Passing Touchdowns allowed to QBs last season. Stafford's last 20 games have seen him fail to clear this line only 3 times total, he's cleared it in back-to-back meetings with the 49ers as well.