49ers vs. Seahawks - NFL Thursday Night Football prop bets Week 6

The NFC West rivalry reignites on Thursday Night Football as the San Francisco 49ers travel north to battle the Seattle Seahawks. With both teams looking to make a statement in a tightly contested division, expect a hard-fought clash with plenty of drama. To help you capitalize on the excitement, we've leveraged the power of our SmartPicks tool to identify 5 prop bets with a history of cashing in.

Fant has been a YAC monster lately, consistently breaking tackles and making defenders miss. The 49ers' defense, while strong overall, can be susceptible to yards after the catch, especially against athletic tight ends like Fant. With a 60% SmartPicks success rate, meaning Fant has topped 20.5 receiving yards in 3 of his last 5 games, this prop bet offers payout potential.

Zach Charbonnet is quickly becoming a dual-threat weapon for the Seahawks. He's not just a runner; he's a reliable receiver out of the backfield. The 49ers, who often focus on shutting down primary receivers, may leave Charbonnet open for check-downs and short passes. With a 100% SmartPicks success rate (he's gone over 13.5 receiving yards in each of his last 5 games), this prop is a strong contender.

For this prop, "Alternative Passing Yards" refers to Geno Smith's passing yards prop alternate to his set line. Smith has been airing it out this season, and the 49ers' defense, which sometimes prioritizes preventing big plays, could give up some chunk yardage through the air. This SmartPicks boasts a 80% success rate (Smith has hit this over in 4 of the last 5 games) and comes with a tempting +162 payout.

Charbonnet is a tough runner who consistently fights for extra yards. The 49ers' front seven is formidable, but Charbonnet's physicality could lead to him breaking tackles and exceeding this total. With a 80% SmartPicks success rate (he's gone over in 4 of the last 5 games) and -113 odds, this prop offers excellent value.

Geno Smith has been a model of efficiency, completing a high percentage of his passes. Against a 49ers defense that can be tough to run against, expect the Seahawks to lean on Smith's arm. He's hit this over in 4 of his last 5 games, giving this SmartPicks an 80% success rate.

Our SmartPicks tool is your secret weapon for smarter betting. These data-driven prop bet recommendations are generated by analyzing various factors, including player performance, team trends, and matchup specifics. But here's the key: the SmartPick success rate is determined by how often that specific prop has hit in the player's last 5 games. This gives you concrete evidence of recent trends to inform your betting decisions.

Looking for trending picks and props for your favorite NFL team? Check out our dedicated NFL team pages for the 2024/2025 season

Our NFL sports betting experts have got you covered. We cover an array of NFL bets:

• NFL Picks
• NFL Parlays
• NFL Props
• NFL Best Bets
• Latest NFL Predictions & News

We also have a full list of the best NFL Sportsbooks, plus an NFL Sports Betting GuideWant to get more involved? Follow us on X/Twitter and be part of the FlashPicks community ⚡